Within the historic fabric of Morro d’Alba, near the beginning of the village in the direction of Jesi, stands the small church built in the first half of the 17th century by the Confraternity of the Most Holy Sacrament, from which it takes its name.

This Confraternity, originally established at the main altar of the Parish Church of San Gaudenzio, sought greater autonomy and, following medieval tradition, repeatedly requested authorization from the Town Council to build its own church. This was granted only in 1614.

According to the diocesan inventory of 1873, the Confraternity dates back to 1450 and was affiliated with the Archconfraternity of the Most Holy Sacrament of the Church of Santa Maria sopra Minerva in Rome in 1632. It remained active locally until the late 1980s and was revitalized in 2005 with the “Ceremony of Vestition” for new members.

Regarding the church itself, above the wooden altar is an oil painting of the Last Supper, dating to the second half of the 17th century, attributed to a local, lesser-known artist who faithfully copied Felice Pellegrini’s Last Supper preserved in the Collegiate Church of Santo Stefano in Castelfidardo.

The church also houses a painted wooden model of the Lauretano shrine from the 18th century. The “Holy House” is rectangular with a gabled roof and a small bell tower; on the roof sit the Madonna and the Child Jesus, blessing. This 18th-century sculpture from Morro d’Alba follows the typology of the Madonna and Child seated on the roof of the sacred house of the Virgin, popularly called “Madonna del Tettarello.”